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Cancer metabolism is intimately linked to drug resistance, which is currently one of the most important challenges in cancer therapy. Recent advancement of novel high-throughput technologies, such as genomics, transcriptomics, proteomics, metabolomics, phenomics, and mega-data bioinformatics (core technology of precision medicine), has been significantly enhanced our understanding of metabolic properties related to malignancy, paving the way for development of biomarker used for early diagnosis and prognosis of cancer, and effective selection of molecular targets for therapeutic interventions. As the burden of cancer is rampantly increasing and posing challenges in early diagnosis and treatment, this international cancer metabolism and therapy conference is planned to hold every other year with the aim of identifying the genuine need in the area and its implementation for patient welfare. We cover a wide range of topics in cancer such as etiology, epidemiology, metabolic reprogramming, environment altered cellular metabolism, cancer prevention and vaccine, new drug development, multidisciplinary treatment i.e. surgical therapy, chemotherapy, and radiotherapy, and cancer stem cell therapy. We believe that cancer therapy and research are in a new era of rapid and significant developments not only in the West but also in Asia as well. Due to newly developed technology, we can readily use many high-tech diagnostic tools, new anticancer drugs, molecular targeting chemotherapy, less invasive and/or less expensive and effective therapy that were unavailable in the near past. Therefore, it is crucial for scientists from all over the world to get together and to share your new ideas and thoughts with each other, especially for young scientists who can communicate openly with the global leaders in the field, investigators, medical and surgical oncologists through your presentations and vigorous discussion. We strongly believe that this conference will help bring about substantial advances in both cancer research and improvement in therapy for all cancer patients. We appreciate all of your participation and hard work to make this conference a great success and we hope to see you all in the beautiful Dalian city in China.